Article. About Kira Pharmaceuticals Kira Pharmaceuticals is a biotechnology company developing complement-targeted therapies to treat immune-mediated diseases. Kira Pharmaceuticals is a biotechnology company developing complement-targeted therapies to treat immune-mediated diseases. Kira's most advanced program, P014, is a first-in-class biologic drug with a unique mechanism of action designed to inhibit both upstream and downstream complement targets. Kira's most advanced program, P014, is a first-in-class biologic drug with a unique mechanism of action designed to inhibit both upstream and downstream complement targets. Dr. Lee comes to the Kira team after serving as Head of Hematology at Alexion Pharmaceuticals, a global company specializing in the development of complement therapies. Kira Pharmaceuticals is a global biotechnology company pioneering a new generation of complement-targeted therapies to treat immune-mediated diseases. Kira Pharmaceuticals Announces First Participant Dosed in Phase 1 Clinical Trial for P014, a Bifunctional Biologic Medicine. By regulating two separate rate-limiting steps in the complement activation cascade that are critical for disease development, P014 provides a powerful, and potentially safer approach to complement inhibition. Kira Pharmaceuticals Announces First Participant Dosed in Phase 1 Clinical Trial for P014, a Bifunctional Biologic Medicine By Kira Pharmaceuticals Feb 2, 2021 "We are thrilled by the rapid progress Kira Pharmaceuticals has made with its lead program, P014, a therapeutic with a truly novel mechanism of action, that will be advancing into the clinic soon," said Matthew Hammond, PhD, Principal at RA Capital Management. Kira’s most advanced program, P014, is a first-in-class biologic molecule with a unique mechanism of action designed to inhibit both upstream and downstream complement targets. It can regulate two separate rate-limiting steps in the complement activation cascade that are critical for disease development. P014 has also been engineered with an extended half-life and potency, with the opportunity for self-administration at home. By regulating two separate rate-limiting steps in the complement activation cascade that are critical for disease development, P014 provides a powerful, and potentially safer approach to complement inhibition. Kira’s most advanced program, P014, is a first-in-class biologic drug with a unique mechanism of action designed to inhibit both upstream and downstream complement targets. This randomized, double blind, placebo-controlled study will evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of escalating single and multiple doses of P014. and SUZHOU, China, Jan. 7, 2021 /PRNewswire/ -- Kira Pharmaceuticals Announces $53.5 Million Series B+ Financing to Advance LOGIC Drug Discovery Platform and Pipeline of Complement-targeted Therapies “We are thrilled by the rapid progress Kira Pharmaceuticals has made with its lead program, P014, a therapeutic with a truly novel mechanism of action, that will be advancing into the clinic soon,” said Matthew Hammond, PhD, Principal at RA Capital Management. CAMBRIDGE, Mass. Kira's most advanced program, P014, is a first-in-class biologic molecule with a unique mechanism of action designed to inhibit both upstream and downstream complement targets. Kira’s most advanced program, P014, is a first-in-class biologic drug with a unique mechanism of action designed to inhibit both upstream and downstream complement targets. Ms. By … The company’s most advanced program, P014, is a first-in-class biologic molecule with a unique mechanism of action designed to inhibit both upstream and downstream complement targets. "We are thrilled by the rapid progress Kira Pharmaceuticals has made with its lead program, P014, a therapeutic with a truly novel mechanism of action, that will be advancing into the clinic soon," said Matthew Hammond, PhD, Principal at RA Capital Management. Kira Pharmaceuticals announced the first healthy volunteer has been successfully dosed in a first-in-human Phase 1 clinical trial for its lead investigational therapy P014. Kira Pharmaceuticals Announces First Participant Dosed in Phase 1 Clinical Trial for P014, a Bifunctional Biologic Medicine PRESS RELEASE PR Newswire Feb. 2, 2021, 01:00 PM Kira Pharmaceuticals, a global biotechnology company pioneering a new generation of complement-targeted therapies to treat immune-mediated diseases, announced the first closing of an oversubscribed $53.5 million Series B+ financing.The financing was co-led by RA Capital Management and Vivo Capital, with participation from Foresite Capital and APlus Partners. FREE Breaking News Alerts from StreetInsider.com! February 2, 2021 GMT . "We are thrilled by the rapid progress Kira Pharmaceuticals has made with its lead program, P014, a therapeutic with a truly novel mechanism of action, that will be advancing into the clinic soon," said Matthew Hammond, PhD, Principal at RA Capital Management. CAMBRIDGE, Mass. Kira has advanced its lead candidate, P014, into the clinic and aims to get two more into human trials over the next 18 months, Beddingfield said in the statement. Kira Pharmaceuticals is a global biotechnology company pioneering a new generation of complement-targeted therapies to treat immune-mediated diseases. and SUZHOU, China, Feb. 23, 2021 /PRNewswire/ -- Kira Pharmaceuticals, a global biotechnology company pioneering a new generation of complement-targeted therapies to treat immune-mediated diseases, today announced the addition of three seasoned pharmaceutical leaders, Kathy He, Richard Lee, MD, and Dana Zhang, MD, to its expanding team. Kira Pharmaceuticals, a global biotechnology company pioneering a new generation of complement-targeted therapies to treat immune-mediated diseases, announced that the first healthy volunteer has been successfully dosed in a first-in-human Phase 1 clinical trial for its lead investigational therapy P014. "We are thrilled by the rapid progress Kira Pharmaceuticals has made with its lead program, P014, a therapeutic with a truly novel mechanism of action, that will be advancing into the clinic soon," said Matthew Hammond, PhD, Principal at RA Capital Management. ... Kira’s lead candidate, P014, targets not … P014 … P014 has … "We are thrilled by the rapid progress Kira Pharmaceuticals has made with its lead program, P014, a therapeutic with a truly novel mechanism of action, that will be advancing into the clinic soon," said Matthew Hammond, PhD, Principal at RA Capital Management. Kira Pharmaceuticals Announces First Participant Dosed in Phase 1 Clinical Trial for P014, a Bifunctional Biologic Medicine . By regulating two separate rate-limiting steps in the complement activation cascade critical for disease development, P014 provides a powerful and selective approach to complement inhibition. and SUZHOU, JIANGSU, China, Feb. 2, 2021 /PRNewswire/ -- Kira Pharmaceuticals Announces First Participant Dosed in Phase 1 Clinical Trial for P014, a Bifunctional Biologic Medicine Kira Pharmaceuticals Announces First Participant Dosed in Phase 1 Clinical Trial for P014, a Bifunctional Biologic Medicine News provided by Kira Pharmaceuticals Enabled by its LOGIC drug discovery platform, … Dr. Lee has also served in clinical and medical affairs leadership roles at several well-known pharmaceutical and biotechnology companies including Roche, Genentech, Millennium/Takeda, Bayer Pharmaceuticals … CAMBRIDGE, Mass. Enter Kira Pharmaceuticals, which launched with $46 million and technology out of the University of Pennsylvania to surmount those hurdles.
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